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Molecular sieves are materials with pores of uniform size and diameter that are similar in size to small molecules; used to separate molecules by size; available in various pore size ranges, with drying solvent indicators, etc.
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Recombinant mouse myelin-associated glycoprotein (MAG/Siglec-4a) produced in HEK293 cells and supplied as a lyophilized, C-terminal 6xHis-tagged protein for biochemical and cell-based assays. Formulated from HEPES or phosphate buffer, the product has a reported molecular weight of 70-120 kDa and demonstrated activity in SH-SY5Y inhibition assays. Store frozen and aliquot to prevent repeated freeze-thaw.
Recombinant mouse MAG/Siglec-4a for functional assays.
Expressed in HEK293 to preserve mammalian post-translational modifications.
C-terminal 6xHis tag for purification and detection.
Lyophilized from buffered saline for stability and transport.
Reported molecular weight 70-120 kDa.
Demonstrated biological activity (ED50 ~3.13 μg/mL in SH-SY5Y assays).
Store at -20°C and aliquot to minimize freeze-thaw cycles.
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Cayman’s 15-PGDH Inhibitor Screening Assay Kit provides a robust and EAsy-to-use platform for identifying novel inhibitors of human 15-PGDH, the enzyme that catalyzes the oxidation of prostaglandins to 15-keto metabolites with reduced biological activity. Measurement of 15-PGDH activity is carried out by monitoring the reduction of NAD+ to NADH. The reduction of NAD+ to NADH is accompanied by an increase in fluorescence at 445 nm following excitation at 340 nm. The potent and reversible 15-PGDH inhibitor ML-148 Assay Reagent is included as a positive control and inhibits 15-PGDH with an IC50 value of 11 nM.
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Recombinant mouse Semaphorin-4A is supplied as a His-tagged, HEK293-expressed protein in a lyophilized 5 μg format for laboratory research. It is designed for studies of plexin-mediated signaling and synaptic development, offering high purity and mammalian-like post-translational modifications to support biochemical and cell-based assays.
Expressed in HEK293 cells for mammalian-like post-translational modifications.
His tag enables straightforward detection and purification.
Lyophilized formulation for extended shelf life and easy storage.
Greater than 95% purity by reducing SDS-PAGE for reliable results.
Molecular weight range 67-95 kDa compatible with SDS-PAGE analysis.
Supplied in a 5 μg size appropriate for small-scale experiments.
Recommended storage at -20°C or -80°C; aliquot after reconstitution.
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AVG-233 (CAS 2151937-80-1) is a small-molecule RNA-dependent RNA polymerase (RdRp) inhibitor used for research on respiratory syncytial virus (RSV). It prevents initiation of the viral polymerase complex and shows nanomolar activity against RSV isolates (reported EC50 = 0.14-0.31 μM). Supplied as an off-white to yellow solid for laboratory use.
Regeneration or ActivationA saturated molecular sieve can be restored to its original capacity by regeneration the principle of which involves changing the conditions surrounding the adsorbent to correspond to a very low equilibrium capacity. In general the greater the difference between the equilibrium capacities of adsorption and regeneration the more rapid and complete the regeneration.The sieve may be regenerated in one of four ways1. Thermal reactivation -The maximum regeneration temperature for Silica is 300C.2. Pressure reactivation3. Passing an appropriate fluid through the gel bed at normal temperature and pressure.4. Displacement of adsorbates by passing a high concentration of molecules in a fluid through the bed.
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Recombinant human Semaphorin-4A Fc fusion protein produced in HEK293 cells and supplied as a sterile, 0.22 μm filtered PBS solution (pH 7.4). The product is provided with analytical data confirming biological activity, an endotoxin specification, and a certificate of analysis reporting high purity. Intended for biochemical and cell-based assays involving SEMA4A interactions and signaling.
Expressed in HEK293 cells as an Fc fusion.
Supplied as PBS buffer, pH 7.4, 0.22 μm filtered.
Endotoxin level <1 EU/μg.
Purity 93.0% as determined by reducing SDS-PAGE.
Suitable for biochemical and cell-based interaction assays.
Store at -80°C and avoid repeated freeze-thaw cycles.
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HFY-4A is a Histone Deacetylase (HDAC) inhibitor. It inhibits breast cancer cell proliferation, migration, and invasion, and induces cell apoptosis and immunogenic cell death (ICD). It also inhibits tumor growth in breast cancer xenograft mouse models.
HDAC inhibitor
Inhibits breast cancer cell proliferation, migration, and invasion
Induces cell apoptosis and immunogenic cell death (ICD)
Inhibits tumor growth in breast cancer xenograft mouse models
Purity: 99.34%
Form: Solid
Color: White to off-white
Soluble in DMSO
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HFY-4A is an HDAC inhibitor that inhibits breast cancer cell proliferation, migration, and invasion, and induces cell apoptosis. It also induces immunogenic cell death (ICD) and inhibits tumor growth in breast cancer xenograft mouse models.
Inhibits breast cancer cell proliferation, migration, and invasion
Induces cell apoptosis
Induces immunogenic cell death (ICD)
Inhibits tumor growth in breast cancer xenograft mouse models
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More